[Objective] In order to ensure the safe circulation of data and promote the development of the data circulation trading market, a standardized unified privacy computing framework is constructed for the interconnection of privacy computing platforms in the data circulation scenario. [Methods] This paper summarizes the development status of privacy computing technologies and platform in recent years, and proposes a unified privacy computing framework based on data circulation scenario with reference to current data circulation problems and data exchange practices. [Results] The unified privacy computing framework proposes a “three-layer architecture, two types of interoperability and one ecology” to achieve business linkage with data exchange platform, unified supervision in the circulation process, and interconnected standard management respectively. Two types of interoperability realize the interconnection between data exchange platform and privacy computing platforms, as well as the interconnection between different privacy computing platforms. One ecology realizes the circulation and transaction ecology of data elements. [Limitations] Private computing technologies are untested for large-scale commercial use; privacy computing technology has yet to strike a balance between computing security and computing efficiency. [Conclusions] The unified privacy computing framework proposed in this paper based on the data circulation transaction scenario is conducive to the close combination of privacy computing technology and data circulation, to maximize the value of data, and to provide a reference for the realization of privacy computing interconnection.